Debunking the “Chemical Imbalance” Theory of Depression

Blogger Phillip Hickey, PhD, has another great Mad in America post debunking the “chemical imbalance” theory of depression based on an article on Florida State University’s DigiNole Commons. The article is a very easy read and I recommend it highly for anyone who has been diagnosed with “depression” or who has ever taken an anti-depressant medication (or for clinicians).

The lie that depression was caused by a chemical imbalance in serotonin levels in the brain was propagated for decades by psychiatrists and Big Pharma. Please, let’s get the word out that this in NOT TRUE! I am so tired of patients and other clinicians continuing to repeat this urban myth.

To tell patients they have a chemical imbalance when this is not true stigmatizes them, promotes a feeling of helplessness that leads to lack of change, and lowers their already-low self-worth.

The public needs to take action to become aware and reject attempts by PCPs and psychiatrists who keep foisting this serotonin myth on them in an effort to sell drugs.

What is Depression?

Depression is merely an expectable reaction to a situation where a person has many thoughts of self-loathing, which lead to chronic high levels of “stress” (aka threat or fear.) The brain reacts to internal messages of self-criticism as a form of threat, which to the brain are processed in the same way as an external physical threat, such as being mugged. This internally generated “fight-or-flight” response cannot be sustained by the brain and body for long periods of time. The body eventually gives up and shuts down physically and numbs out emotionally, with “symptoms” of lack of motivation, excessive sleep, sadness, worthlessness, helplessness, hopelessness, etc.

Perhaps one day some brain chemical cause of depression might be discovered. But until then, please stop repeating the lie that unhealthy serotonin levels cause depression. Because the above explanation IS actually based on science!